And again, you are Welcome.
To be clear, the nebulized method IS very effective for the quicker relief they offer with meds like Albuterol and STEROIDS. That's all we get in the hospital for a cure anyway. OHTUVYRE is just NOT that same type of drug.

The level of inflammatory cells in the body will vary greatly between patients. That is why the state of the circulatory system is key in being eligible for the new meds. If you don't have the blood test to show higher inflammation levels, the insurance company will deny. They approve the pill based off of other factors, like recent flare-ups and ER visits.
take Care.

Hi Phyllis. Here is my response to your question. If you click on the name of this NEW medication OHTUVAYRE it is generally described as an Anti-Inflammatory and Bronchidialator. The ingredients are known as PDE-3 and PDE-4 and Google will give you the long name and an explanation of how these act on the body. Their PDE-4 ingredient is probably very similar to a previous med named Daliresp (or Roflumilast in generic form. You can click on those names here too.)

From my research and experience, inflammation is a cellular disorder and can be controlled by medicine IN your system. This is why it is important to take meds in full dose and with regular timing. Other meds work more "instantly" which is why I disagree with OHTUVYRE being a Bronchidialator. The best way to achieve that is with things like Albuterol puffer which goes strait into the lungs.

My older med Roflumilast is much less expensive since it has gone to generic. Don't be surprised if your insurance company suggests that route instead of the new guy. Besides, this is the only "Home Med" the hospital would let me have while in the ICU. Everything else was according to their treatment protocol.

All that to say other than TRIALS, the med is too new to really know if the results will accrue you as well. That is what my DOC told me when I asked last JUNE when it was first released. He had not heard of it yet! 🤔 We decided to wait and see what others report in the meantime. Since he trusts me staying informed, we talked about other things. I told him I had already invested in shares of the VRNA company that makes it. He smiled 🤑. I can't wait to see his face when I go back in a few weeks. The stock has doubled since then and I feel much better too!!
(This is not medical or financial advice - AND your mileage WILL vary). be Well. . .and well informed.

Thank you. I did a bit of research and was dismayed to find that it was too new to know how many were affected negatively by it. Most people who took it said they saw no change in their symptoms. I’m not comfortable with a med this new. Plus, I really prefer an inhaler as opposed to a bulky nebulizer. Thank you again.